Tuesday, November 13, 2007

Ascorbate Oxidative Therapy

Ascorbate Oxidative Therapy
Vitamin C used to selectively kill cancer cells.
Almost a Magic Bullet for Cancer Care


Ascorbate Oxidative Therapy is the use of buffered Vitamin C intravenously in large gram doses to induce a free radical attack that can selectively kill human cancer cells Normal human cells can withstand this free radical assault but human cancer cells cannot!

The U.S. National Institute of Health reported that Pharmacologic ascorbic acid concentrations selectively kill cancer cells: Action as a pro-drug to deliver hydrogen peroxide to tissues. Qi Chen, Michael Graham Espey, Murali C. Krishna, James B. Mitchell, Christopher P. Corpe, Garry R. Buettner, Emily Shacter, and Mark Levine state that:

Taken together, these data indicate that ascorbate at concentrations achieved only by i.v. administration may be a pro-drug for formation of H2O2, and that blood can be a delivery system of the pro-drug to tissues. These findings give plausibility to i.v. ascorbic acid in cancer treatment, and have unexpected implications for treatment of infections where H2O2 may be beneficial.



http://www.pnas.org/cgi/content/abstract/102/38/13604
http://www.pnas.org/cgi/reprint/102/38/13604


Clinical Studies have gathered that buffered Vitamin C when administered intravenously in large doses can act as to selectively burn out human cancer cells. At serum concentration in excess of 350 to 400 mg/dl Vitamin C acts to selectively kill cancer cells.

Ascorbate Oxidative Therapy is able to selectively kill cancer cells because cancer cells are generally deficient in the enzyme catalase. Catalase is an enzyme used to catalyze the breakdown of hydrogen peroxide to water and oxygen. Cancer cells being relatively deficient in this enzyme easily suffer from free radical assault; whereas, normal human cells are relatively safe and are even enhanced by this Vitamin C therapy.

This provides an excellent stand alone nutritional chemotherapy for some cancer patients and a health building and restoring wellness adjunct for other cancer patients.

Vitamin C has been a very controversial nutrient. When something is controversial that means that there is good science on both sides of the issue. I don’t know why reasonable and intelligent people would ignore good science.

The medical hoax against Vitamin C included the high risk of developing kidney stones. This has never been documented clinically even in studies involving patients who were medically stone formers. Granted the use of even small amounts of Vitamin C changes the blood and kidney chemistry but this may be a sign of restored vitality and wellness. On the other hand, if we haven’t seen kidney stone development clinically along with the use of Vitamin C then pretty much we can conclude that it is NOT a big risk.

Vitamin C is generally known as an anti-oxidant. However, in larger quantities and in higher concentrations Vitamin C has a mass action effect that results in the generation of peroxide free radicals.

When the serum concentration of Vitamin C surpasses 350 to 400 mg per dl free radicals begin to destroy the catalase deficient cancer cells.

Meanwhile instead of untoward side effects, Normal human cells are enhanced and revitalized by this therapy. It helps purify the blood, super oxygenates the blood even reversing carbon monoxide binding to hemoglobin, improve circulation to the tissues, and detoxify the liver and kidneys, powers up the bacteria killing ability of immune cells and more.

Patients need a full medical workup before undertaking this therapy. About 1% of the population cannot use high dose Vitamin C due to a genetic congenital enzyme deficiency involving Glucose 6-Phospahate Dehydrogenase (G6PD). This needs to be checked with laboratory testing prior to using even oral Vitamin C. Persons deficient in Glucose 6-Phospahate Dehydrogenase (G6PD) would die from fatal reaction to the Vitamin C. Ten grams of Vitamin C given orally has been shown to be lethal to 1% of cancer patients. Check the G6PD levels before considering or beginning any therapy.

This needs to be done under a physician’s care and supervision. But don’t expect it from an Oncologist. Not yet, as it’s not part of their clinical protocols. A clinical protocol for this therapy can be found at http://brightspot.org/cresearch/intravenousc2.shtml